9-Fluorenylmethyl (Fm) Disulfides: Biomimetic Precursors for Persulfides
نویسندگان
چکیده
منابع مشابه
9-Fluorenylmethyl (Fm) Disulfides: Biomimetic Precursors for Persulfides
The development of a functional disulfide, FmSSPy-A (Fm = 9-fluorenylmethyl; Py = pyridinyl), is reported. It can effectively convert small molecule and protein thiols (-SH) to form -S-SFm adducts under mild conditions. This method allows for a H2S-free and biomimetic protocol to generate highly reactive persulfides (in their anionic forms). The high nucleophilicity of persulfides toward a numb...
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ژورنال
عنوان ژورنال: Organic Letters
سال: 2016
ISSN: 1523-7060,1523-7052
DOI: 10.1021/acs.orglett.5b03557